MIDAX

Midax (Eye Drops)
(Tropicamide)

 

COMPOSITION
Each ml contains: in 0.5% solution tropicamide 5 mg, in 1.0% solution tropicamide 10 mg.

THERAPEUTIC INDICATIONS
- If mydriasis is necessary for eye ground investigation and crystalline lens condition estimation;
- If accommodative paralysis is necessary for refraction investigation;
- Hypersensitivity to other drugs, dilatating pupil (atropine, scopolamine);
Prior to surgical operations:
- crystalline lens surgery;
- retina laser therapy;
- retinal and vitreous humor surgery.
With therapeutic purposes:
- As a component of complex therapy of inflammatory eye diseases and during postoperative period for synechia development prophylaxis.
- In composition of complex therapy of inflammatory eye diseases and synechia.

CONTRAINDICATIONS
- Glaucoma (especially closed-angle and mixed primary);
- Known hypersensitivity to any of drug components.

ADVERSE EFFECTS
From visual organs: intraocular pressure increase; visual acuity impairment; photophobia. Burning and epiphora continuing for 15-20 seconds, are possible immediately after drug instillation. From CNS: sometimes – psychotic symptoms, behavioral disorders (especially in children and teenagers); headaches (in adults). From cardiovascular system: circulatory and respiratory deficiency symptoms (especially in children and teenagers); tachycardia (in adults). Other: dry mouth, allergic reactions.

DOSAGE AND ADMINISTRATION
The preparation is instilled into conjunctival sac. For papillary dilatation 1 drop of 1.0% or 2 drops of 0.5% solution of Midax are instilled (in 5 minutes intervals). Ophthalmoscopy may be carried out after 10 minutes. If the effect is insufficient (very high light intensity, application for back synechia rupture), it may be used together with phenylephrine.To achieve accommodative paralysis (at refraction investigation) 1 drop of 1.0% Midax solution is instilled 6 times in 6-12 minutes intervals. The investigation should be preferably carried out during 25-30 minutes from the moment of last drug instillation. 0.5% eye drops should be applied in nursing children and children before 6 years of age. In some cases systemic anticholinergic effects of Midax were observed in premature children, which increase during repeated application. These adverse events can be avoided without efficacy decrease at the expense of prescription drug dilution with isotonic solution of sodium chloride (1:1). It is necessary to press lachrymal canals during drug instillation in order to limit excessive tropicamide absorption and prevent systemic anticholinergiс drug effect. Dosage regimen for therapeutic purposes is established individually (depending on patient condition).

PRECAUTIONS
Before Midax application it is necessary to remove soft contact lenses. They can be reinserted again not earlier than after 30 minutes from the instillation moment.

PREGNANCY AND LACTATION
Midax application at pregnancy is possible only in cases, when expected benefit for mother exceeds potential risk for fetus. The drug should be administered with care during lactation period.

MANUFACTURED FORM
10 ml plastic vial with dropping stopper and screw cap, supplied with guard ring. Vial in carton box with packaging leaflet.